Worldwide Alzheimer's disease neuroimaging initiative

Maria C. Carrillo, Lisa J. Bain, Giovanni B. Frisoni, Michael W. Weiner

Research output: Contribution to journalArticlepeer-review

Abstract

The Alzheimer's Disease Neuroimaging Initiative (ADNI) was launched in 2003 to speed drug development by validating imaging and blood/cerebrospinal fluid biomarkers for Alzheimer's disease clinical treatment trials. ADNI is a naturalistic (nontreatment) multisite longitudinal study. A true public-private partnership, the first phase of ADNI (ADNI 1) set a new standard for data sharing without embargo. In addition, it has been extended to 2017 by additional funding (North American-ADNI Grand Opportunities and ADNI 2) as well as multiple projects around the world, collectively known as Worldwide ADNI (WW-ADNI). The goal of WW-ADNI is to harmonize projects and results across different geographical sites and to encourage and harmonize data management and availability to investigators around the world. WW-ADNI projects are currently underway in North America, Europe, Japan, Australia, Korea, Taiwan, and Argentina, with a nascent program in China and a possible future program in Brazil.

Original languageEnglish
Pages (from-to)337-342
Number of pages6
JournalAlzheimer's and Dementia
Volume8
Issue number4
DOIs
Publication statusPublished - Jul 2012

Keywords

  • Alzheimer's disease
  • Biomarkers
  • Neuroimaging

ASJC Scopus subject areas

  • Health Policy
  • Epidemiology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience
  • Clinical Neurology

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