Worsening of regional postinfarction asynergy after dipyridamole

Does it reflect ischemic viable myocardium?

M. Galli, W. Bencivelli, P. Giannuzzi, F. Santoro, L. Tavazzi

Research output: Contribution to journalArticle

Abstract

In patients with myocardial infarction, a further impairment induced by dipyridamole in an asynergic ventricular segment could either reflect a condition of residual ischemia or the mechanical consequences of hemodynamic changes. To investigate the relative role of these factors, 46 patients with recent infarction were subjected to a dipyridamole test in association with a thallium scan and echocardiographic monitoring. Contractility and perfusion in nine matching segments were compared; a reversible thallium uptake defect was taken as evidence of regional ischemia. In the baseline state 166 of 414 segments were classified as hypokinetic (n = 85) or akinetic (n = 81) by echocardiography; the condition of 92 of these worsened after dipyridamole (63 passing from hypokinesia to akinesia and 29 from akinesia to dyskinesia). Thallium scan showed a reversible defect in 57 (62%) of the segments, but in only 15 (20%) of those with stable asynergy (p

Original languageEnglish
Pages (from-to)240-247
Number of pages8
JournalAmerican Journal of Noninvasive Cardiology
Volume5
Issue number4
Publication statusPublished - 1991

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Dipyridamole
Thallium
Myocardium
Ischemia
Hypokinesia
Dyskinesias
Infarction
Echocardiography
Perfusion
Hemodynamics
Myocardial Infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Worsening of regional postinfarction asynergy after dipyridamole : Does it reflect ischemic viable myocardium? / Galli, M.; Bencivelli, W.; Giannuzzi, P.; Santoro, F.; Tavazzi, L.

In: American Journal of Noninvasive Cardiology, Vol. 5, No. 4, 1991, p. 240-247.

Research output: Contribution to journalArticle

Galli, M, Bencivelli, W, Giannuzzi, P, Santoro, F & Tavazzi, L 1991, 'Worsening of regional postinfarction asynergy after dipyridamole: Does it reflect ischemic viable myocardium?', American Journal of Noninvasive Cardiology, vol. 5, no. 4, pp. 240-247.
Galli, M. ; Bencivelli, W. ; Giannuzzi, P. ; Santoro, F. ; Tavazzi, L. / Worsening of regional postinfarction asynergy after dipyridamole : Does it reflect ischemic viable myocardium?. In: American Journal of Noninvasive Cardiology. 1991 ; Vol. 5, No. 4. pp. 240-247.
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