Farmaci e utilizzo "wrong-label" in pediatria - L'esempio del paracetamolo, del salbutamolo e dell'amoxicillina

Translated title of the contribution: Wrong-label drug use in paediatrics: The examples of acetaminophen, salbutamol and amoxicillin

Ines L'Erario, Anna Di Benedetto, Jenny Bua, Stefania Norbedo, Egidio Barbi, Federico Marchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Two thirds of the drugs prescribed for children are off-label. However, off-label is not synonymous with incorrect, since it often represents the most rational, evidence-based therapy. One aspect of the off-label problem in paediatrics depends on the lack of updating the drugs specific Summary Product Characteristics (SPC). This is a frequent problem in Italy. The Authors give the example of three of the most commonly prescribed drugs in paediatrics (acetaminophen, salbutamol and amoxicillin), the SPC which recommends wrong dosages compared to those based on the to-date evidence and recommended by clinical guidelines ("wrong-label"). Reviewing and updating of SPC should be one of the priorities to tackle the off-label problem in the Italian reality.

Translated title of the contributionWrong-label drug use in paediatrics: The examples of acetaminophen, salbutamol and amoxicillin
Original languageItalian
Pages (from-to)580-585
Number of pages6
JournalMedico e Bambino
Volume26
Issue number9
Publication statusPublished - Nov 30 2007

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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