X-ray diffraction analysis of bone-cement interface in failed hip arthroplasties

L. Savarino, S. Stea, D. Granchi, M. E. Donati, G. Paganetto, A. Pizzoferrato, A. Toni

Research output: Contribution to journalArticlepeer-review


This study was focused on the bone tissue response to cement in failed hip joint prostheses. The investigation was carried out by means of micro-beam X-ray diffractometric (XRD) analysis of the bone-cement interface. Nine cemented prostheses retrieved because of loosening were studied. This research has demonstrated that the newly formed bone close to the cement in loosened prostheses showed a normal apatitic structure, though bone tissue was often found poorly mineralized. In contrast, in stable prostheses well-mineralized bone was observed. In both cases, however, the bone apatite lattice at the interface was shown not to be different from pre-existing bone. The authors conclude that the mineralization process close to the cement can be thoroughly evaluated by micro-beam XRD techniques.

Original languageEnglish
Pages (from-to)644-646
Number of pages3
JournalJournal of Materials Science: Materials in Medicine
Issue number9-10
Publication statusPublished - Sep 1994

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering(all)
  • Biophysics


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