X-ray diffraction of newly formed bone close to alumina- or hydroxyapatite-coated femoral stem

L. Savarino, E. Cenni, S. Stea, M. E. Donati, G. Paganetto, A. Moroni, A. Toni, A. Pizzoferrato

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The study was focused on the bone tissue response to two types of ceramic coating [alumina and hydroxyapatite (HA)] obtained with a plasma-spray technique. The HA coating was performed on titanium stems, while the alumina coating was on chromium-cobalt-molybdenum stems. The investigation was carried out by means of micro-area X-ray diffractometric analyses and microdiffractometric analyses at the bone-implant interface. Moreover, the coating before and after implantation was analysed by means of the conventional powder X-ray diffractometric technique. This study demonstrated that 1 yr after implantation in animals the newly formed bone adjacent to the HA-coated hip prosthesis stems was mineralized as much as the preexisting bone, while 24-64 months after surgery in humans the newly formed bone close to the alumina-coated hip prosthesis stems showed a lamellar and Haversian structure strongly demineralized, probably due to the release of aluminium ions from the alumina covering. The authors conclude that the X-ray diffraction allows the evaluation of the structural modifications of the ceramic coating, the bone formation rate close to the coating and the chemical nature of the particles released from the coating.

Original languageEnglish
Pages (from-to)900-905
Number of pages6
JournalBiomaterials
Volume14
Issue number12
DOIs
Publication statusPublished - 1993

Fingerprint

Aluminum Oxide
Durapatite
Thigh
Hydroxyapatite
X-Ray Diffraction
Bone
Alumina
Bone and Bones
X ray diffraction
Hip Prosthesis
Coatings
Hip prostheses
Ceramic coatings
X-Rays
Molybdenum
Ceramics
Chromium
Cobalt
Titanium
Aluminum

Keywords

  • alumina
  • hydroxyapatite
  • mineralization
  • Prostheses
  • X-ray diffraction

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Savarino, L., Cenni, E., Stea, S., Donati, M. E., Paganetto, G., Moroni, A., ... Pizzoferrato, A. (1993). X-ray diffraction of newly formed bone close to alumina- or hydroxyapatite-coated femoral stem. Biomaterials, 14(12), 900-905. https://doi.org/10.1016/0142-9612(93)90131-K

X-ray diffraction of newly formed bone close to alumina- or hydroxyapatite-coated femoral stem. / Savarino, L.; Cenni, E.; Stea, S.; Donati, M. E.; Paganetto, G.; Moroni, A.; Toni, A.; Pizzoferrato, A.

In: Biomaterials, Vol. 14, No. 12, 1993, p. 900-905.

Research output: Contribution to journalArticle

Savarino, L, Cenni, E, Stea, S, Donati, ME, Paganetto, G, Moroni, A, Toni, A & Pizzoferrato, A 1993, 'X-ray diffraction of newly formed bone close to alumina- or hydroxyapatite-coated femoral stem', Biomaterials, vol. 14, no. 12, pp. 900-905. https://doi.org/10.1016/0142-9612(93)90131-K
Savarino, L. ; Cenni, E. ; Stea, S. ; Donati, M. E. ; Paganetto, G. ; Moroni, A. ; Toni, A. ; Pizzoferrato, A. / X-ray diffraction of newly formed bone close to alumina- or hydroxyapatite-coated femoral stem. In: Biomaterials. 1993 ; Vol. 14, No. 12. pp. 900-905.
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