X-rays Compton detectors for Biomedical application

Paolo Rossi, Giuseppe Baldazzi, Andrea Battistella, Michele Bello, Dante Bollini, Valter Bonvicini, Cristiano Lino Fontana, Gisella Gennaro, Giuliano Moschini, Francesco Navarria, Alexander Rashevsky, Nikolay Uzunov, Gianluigi Zampa, Nicola Zampa, Andrea Vacchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Collimators are usually needed to image sources emitting X-rays that cannot be focused. Alternately, one may employ a Compton Camera (CC) and measure the direction of the incident X-ray by letting it interact with a thin solid, liquid or gaseous material (Tracker) and determine the scattering angle. With respect to collimated cameras, CCs allow higher gamma-ray efficiency in spite of lighter geometry, and may feature comparable spatial resolution. CCs are better when the X-ray energy is high and small setups are required. We review current applications of CCs to Gamma Ray Astronomy and Biomedical systems stressing advantages and drawbacks. As an example, we focus on a particular CC we are developing, which is designed to image small animals administered with marked pharmaceuticals, and assess the bio-distribution and targeting capability of these latter. This camera has to address some requirements: relatively high activity of the imaged objects; detection of gamma-rays of different energies that may range from 140keV (Tc99m) to 511 keV; presence of gamma and beta radiation with energies up to 2MeV in case of 188Re. The camera consists of a thin position-sensitive Silicon Drift Detector as Tracker, and a further downstream position-sensitive system employing scintillating crystals and a multi-anode photo-multiplier (Calorimeter). The choice of crystal, pixel size, and detector geometry has been driven by measurements and simulations with the tracking code GEANT4. Spatial resolution, efficiency and scope are discussed.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages356-360
Number of pages5
Volume1336
DOIs
Publication statusPublished - 2011
Event21st International Conference on Application of Accelerators in Research and Industry, CAARI 2010 - Fort Worth, TX, United States
Duration: Aug 8 2010Aug 13 2010

Other

Other21st International Conference on Application of Accelerators in Research and Industry, CAARI 2010
Country/TerritoryUnited States
CityFort Worth, TX
Period8/8/108/13/10

Keywords

  • Compton camera
  • Gamma detectors
  • Molecular imaging
  • Small animals SPET

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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