Xenopus laevis embryos share antigens with zebrafish embryos and with human malignant neoplasms

P. M. Biava, A. Monguzzi, D. Bonsignorio, A. Frosi, S. Sell, J. V. Klavins

Research output: Contribution to journalArticle

Abstract

Previous experiments have demonstrated that antigens present in Xenopus laevis embryos are shared with human malignant neoplasms. In fact it is known that antisera raised in rabbit against pellet and supernatant fractions of Xenopus laevis embryos react to different antigens present in human tumors. The aim of the the present study was to evaluate whether these antisera react also to different antigens contained in zebrafish embryos at different stages of cell differentiation. This was done with the agar-gel immunodiffusion method performed according to an already described protocol. The results that we obtained show that both antisera raised in against pellet and supernatant fractions of Xenopus laevis embryos react to antigens of zebrafish at different stages of cell differentiation.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalJournal of Tumor Marker Oncology
Volume16
Issue number3
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Cancer Research

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    Biava, P. M., Monguzzi, A., Bonsignorio, D., Frosi, A., Sell, S., & Klavins, J. V. (2001). Xenopus laevis embryos share antigens with zebrafish embryos and with human malignant neoplasms. Journal of Tumor Marker Oncology, 16(3), 203-206.