Xotx1 maternal transcripts are vegetally localized in Xenopus laevis oocytes

Maria Pannese, Rachele Cagliani, Celia Leonor Pardini, Edoardo Boncinelli

Research output: Contribution to journalArticlepeer-review

Abstract

Xotx1 is a Xenopus homeobox gene related to the Drosophila gene orthodenticle (otd). We previously reported that Xotx1 transcripts are already present in unfertilized egg. Here we report that maternal Xotx1 mRNA is vegetally localized during oogenesis. In stage II oocytes Xotx1 transcripts are localized within the mitochondrial cloud, in a perinuclear position; later on, they are translocated to the vegetal cortex within the mitochondrial cloud. We also observed that in stage III oocytes the expression domain of Wnt11 is contained within the one of Xotx1 while, at stage IV, the Xotx1 expression domain is contained within the one of Vg1. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)111-114
Number of pages4
JournalMechanisms of Development
Volume90
Issue number1
DOIs
Publication statusPublished - Jan 1 2000

Keywords

  • Development
  • Homeobox
  • Localized mRNA
  • Oocyte polarity
  • Otx1
  • Vegetal cortex
  • Xenopus laevis

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

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