Y chromosome duplication: A minor route evolutive pattern in CML

G. Alimena, F. Mandelli, A. Montuoro, R. Gastaldi, B. Dallapiccola

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our cases and in previously reported individuals, suggests preliminary conclusions about the prognostic significance of this aneuploidy. Y chromosome gain does not seem to represent per se an unfavourable event, unless it is associated with additional chromosome change.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalActa Haematologica
Volume61
Issue number6
Publication statusPublished - 1979

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Chromosome Duplication
Y Chromosome
Aneuploidy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cytogenetics
Chromosomes
Survival

ASJC Scopus subject areas

  • Hematology

Cite this

Alimena, G., Mandelli, F., Montuoro, A., Gastaldi, R., & Dallapiccola, B. (1979). Y chromosome duplication: A minor route evolutive pattern in CML. Acta Haematologica, 61(6), 310-316.

Y chromosome duplication : A minor route evolutive pattern in CML. / Alimena, G.; Mandelli, F.; Montuoro, A.; Gastaldi, R.; Dallapiccola, B.

In: Acta Haematologica, Vol. 61, No. 6, 1979, p. 310-316.

Research output: Contribution to journalArticle

Alimena, G, Mandelli, F, Montuoro, A, Gastaldi, R & Dallapiccola, B 1979, 'Y chromosome duplication: A minor route evolutive pattern in CML', Acta Haematologica, vol. 61, no. 6, pp. 310-316.
Alimena G, Mandelli F, Montuoro A, Gastaldi R, Dallapiccola B. Y chromosome duplication: A minor route evolutive pattern in CML. Acta Haematologica. 1979;61(6):310-316.
Alimena, G. ; Mandelli, F. ; Montuoro, A. ; Gastaldi, R. ; Dallapiccola, B. / Y chromosome duplication : A minor route evolutive pattern in CML. In: Acta Haematologica. 1979 ; Vol. 61, No. 6. pp. 310-316.
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