Y chromosome duplication: A minor route evolutive pattern in CML

G. Alimena, F. Mandelli, A. Montuoro, R. Gastaldi, B. Dallapiccola

Research output: Contribution to journalArticlepeer-review


2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our cases and in previously reported individuals, suggests preliminary conclusions about the prognostic significance of this aneuploidy. Y chromosome gain does not seem to represent per se an unfavourable event, unless it is associated with additional chromosome change.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalActa Haematologica
Issue number6
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Hematology


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