Y chromosome duplication: A minor route evolutive pattern in CML

G. Alimena, F. Mandelli, A. Montuoro, R. Gastaldi, B. Dallapiccola

Research output: Contribution to journalArticle

Abstract

2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our cases and in previously reported individuals, suggests preliminary conclusions about the prognostic significance of this aneuploidy. Y chromosome gain does not seem to represent per se an unfavourable event, unless it is associated with additional chromosome change.

Original languageEnglish
Pages (from-to)310-316
Number of pages7
JournalActa Haematologica
Volume61
Issue number6
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Y chromosome duplication: A minor route evolutive pattern in CML'. Together they form a unique fingerprint.

  • Cite this

    Alimena, G., Mandelli, F., Montuoro, A., Gastaldi, R., & Dallapiccola, B. (1979). Y chromosome duplication: A minor route evolutive pattern in CML. Acta Haematologica, 61(6), 310-316.