Y-chromosome short tandem repeat (STR) haplotypes in a Campania population sample

Giuseppe Calcagno, Giuseppe Labruna, Lucia Sacchetti

Research output: Contribution to journalArticlepeer-review

Abstract

Given the lack of information about Y haplotypes for Campania (southern Italy), we analyzed eight Y short tandem repeats in a sample of males from this region with the aim of establishing a Y-haplotype database that can be used for forensic purposes. The eight Y short tandem repeats were amplified by two PCR multiplex reactions: multiplex A for Ioci DYS19, DYS385, DYS392 and DYS393, and multiplex B for DYS389 I and II, DYS390, DYS391 and DYS385. The proportion of unique haplotypes was 100% (108 Y-chromosome haplotypes in 108 unrelated males) and the haplotype diversity discrimination index was 0.99. These data reflect the high heterogeneity of male lineage in our population and are similar to those obtained in other regions of southern Italy.

Original languageEnglish
Pages (from-to)163-166
Number of pages4
JournalClinical Chemistry and Laboratory Medicine
Volume43
Issue number2
DOIs
Publication statusPublished - 2005

Keywords

  • Capillary electrophoresis
  • Haplotype
  • Short tandem repeats
  • Y chromosome

ASJC Scopus subject areas

  • Clinical Biochemistry

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