Costo sociale annuo della dispepsia funzionale dopo l'eradicazione dell'Helicobacter pylori. Risultati di un'indagine in centri di endoscopia digestiva

Translated title of the contribution: Yearly social cost of functional dyspepsia after Helicobacter pylori eradication

Giorgio Lorenzo Colombo, M. Caruggi, M. Vinci, P. Nardini, S. Casalini, S. Adamo, M. Amuso, D. Angioli, G. Bagnalasta, G. Benedetti, G. Bianchi Porro, M. Biagini, U. Bigazzi, P. Bodini, R. Briglia, P. Brosolo, G. Budillon, A. Candela, A. Capria, L. CapursoA. Cardelli, V. Casale, T. Casetti, D. Cattaneo, F. Cerrai, R. Cesaroni, F. Chilovi, R. Corinaldesi, A. Craxì, M. Curzio, A. D'Ambrosi, V. D'Ambruoso, M. D'Ayala Valva, L. De Blasi, M. De Filippi, B. De Luca, B. De Spagnolis, M. Del Piano, C. Del Vecchio Blanco, P. Dell'Abate, M. Di Blasi, M. Di Stasi, E. D'Ingianna, D. Faleo, A. Ferrara, G. Ferrini, G. Franzé, G. Frosini, E. Gaia, R. Galeazzi, S. Giaccari, A. Giglio, F. P. Gioè, M. Grassini, L. Graziadei, S. Gullini, M. La Barbera, P. Loriga, T. Luisi, M. Magalini, G. Magrì, P. Maiolo, A. Malesci, M. Manildo, S. Marchi, A. Maurano, U. Mercati, P. Michetti, F. Milesi, F. Molinari, S. Morini, L. Nanfitò, G. Novelli, N. Olivari, F. Oliverio, F. Pacini, S. Pallio, G. Pasquini, A. Paterlini, A. Pera, M. Perego, G. Pracanica, A. Prada, U. Privitera, S. Recchia, G. Riegler, M. Rizzetto, F. Rocca, E. Roda, M. Romano, M. Rubbiani, A. Russo, A. Saggioro, V. Savarino, G. Scarpulla, C. Schiavone, D. Spotti, G. Sturniolo, R. Suriani, C. Surrenti, P. Usai, G. Verdianelli, G. Verros, S. Vigneri, A. Zambelli, G. Zaninotto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The aim of this study was to evaluate socio-demographic and clinical characteristics of dyspeptic patients in Italy after the eradication of Helicobacter pylori infection and to evaluate the impact of this syndrome on daily activities, on loss of production, and, finally, to estimate its cost for both National Health Service and society. Design: An observational, prospective, one-year, multicenter study was conducted from April 1999 to April 2002 under the aegis of the Italian study group of digestive tract motility (GISMAD). The study was based on 577 consecutive functional dyspeptic patients after eradication of H. pylori. Data were collected by a Case Report Form (CRF). Setting: 91 Centres of Digestive Endoscopy (CED), all located in Italy. Results: The mean age of the 577 dyspeptic patients enrolled in the study was 52 yrs.±14 (13.3% was younger than 40 yrs old; mostly females: 56.7%). Sixty point seven percent of patients met expenses related with the treatment of dyspepsia. Patients were stratified into four groups according to their prevalent symptoms: ulcer-like (UL), dismotility-like (DL), reflux-like (RL) and 'other'. Annual mean cost estimated for each patient was € 145.54, with differences between females and males ( € 168.95 vs € 114.91 respectively). "RL" patients resulted at the highest cost (€ 204.32). Total costs were divided into health related costs (€ 60.87) and loss of productivity (€ 84.67), the latter being mostly related absences (21%). Conclusions: During a follow-up period of 12 months, in each group there was a clear evidence of both a reduction of negative influence of dyspeptic symptoms on the patients' activities and a decrease of the mean cost for the treatment of dyspepsia. "RL" group presents cost 30% higher when compared with "UL" and "DL" groups, and 90% higher when compared with "other".

Original languageItalian
Pages (from-to)27-42
Number of pages16
JournalPharmacoEconomics - Italian Research Articles
Volume7
Issue number1
Publication statusPublished - 2005

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Dyspepsia
Helicobacter pylori
Costs and Cost Analysis
Health Care Costs
Italy
Ulcer
National Health Programs
Helicobacter Infections
Endoscopy
Multicenter Studies
Gastrointestinal Tract
Demography

ASJC Scopus subject areas

  • Pharmacology
  • Health Policy

Cite this

Costo sociale annuo della dispepsia funzionale dopo l'eradicazione dell'Helicobacter pylori. Risultati di un'indagine in centri di endoscopia digestiva. / Colombo, Giorgio Lorenzo; Caruggi, M.; Vinci, M.; Nardini, P.; Casalini, S.; Adamo, S.; Amuso, M.; Angioli, D.; Bagnalasta, G.; Benedetti, G.; Bianchi Porro, G.; Biagini, M.; Bigazzi, U.; Bodini, P.; Briglia, R.; Brosolo, P.; Budillon, G.; Candela, A.; Capria, A.; Capurso, L.; Cardelli, A.; Casale, V.; Casetti, T.; Cattaneo, D.; Cerrai, F.; Cesaroni, R.; Chilovi, F.; Corinaldesi, R.; Craxì, A.; Curzio, M.; D'Ambrosi, A.; D'Ambruoso, V.; D'Ayala Valva, M.; De Blasi, L.; De Filippi, M.; De Luca, B.; De Spagnolis, B.; Del Piano, M.; Del Vecchio Blanco, C.; Dell'Abate, P.; Di Blasi, M.; Di Stasi, M.; D'Ingianna, E.; Faleo, D.; Ferrara, A.; Ferrini, G.; Franzé, G.; Frosini, G.; Gaia, E.; Galeazzi, R.; Giaccari, S.; Giglio, A.; Gioè, F. P.; Grassini, M.; Graziadei, L.; Gullini, S.; La Barbera, M.; Loriga, P.; Luisi, T.; Magalini, M.; Magrì, G.; Maiolo, P.; Malesci, A.; Manildo, M.; Marchi, S.; Maurano, A.; Mercati, U.; Michetti, P.; Milesi, F.; Molinari, F.; Morini, S.; Nanfitò, L.; Novelli, G.; Olivari, N.; Oliverio, F.; Pacini, F.; Pallio, S.; Pasquini, G.; Paterlini, A.; Pera, A.; Perego, M.; Pracanica, G.; Prada, A.; Privitera, U.; Recchia, S.; Riegler, G.; Rizzetto, M.; Rocca, F.; Roda, E.; Romano, M.; Rubbiani, M.; Russo, A.; Saggioro, A.; Savarino, V.; Scarpulla, G.; Schiavone, C.; Spotti, D.; Sturniolo, G.; Suriani, R.; Surrenti, C.; Usai, P.; Verdianelli, G.; Verros, G.; Vigneri, S.; Zambelli, A.; Zaninotto, G.

In: PharmacoEconomics - Italian Research Articles, Vol. 7, No. 1, 2005, p. 27-42.

Research output: Contribution to journalArticle

Colombo, GL, Caruggi, M, Vinci, M, Nardini, P, Casalini, S, Adamo, S, Amuso, M, Angioli, D, Bagnalasta, G, Benedetti, G, Bianchi Porro, G, Biagini, M, Bigazzi, U, Bodini, P, Briglia, R, Brosolo, P, Budillon, G, Candela, A, Capria, A, Capurso, L, Cardelli, A, Casale, V, Casetti, T, Cattaneo, D, Cerrai, F, Cesaroni, R, Chilovi, F, Corinaldesi, R, Craxì, A, Curzio, M, D'Ambrosi, A, D'Ambruoso, V, D'Ayala Valva, M, De Blasi, L, De Filippi, M, De Luca, B, De Spagnolis, B, Del Piano, M, Del Vecchio Blanco, C, Dell'Abate, P, Di Blasi, M, Di Stasi, M, D'Ingianna, E, Faleo, D, Ferrara, A, Ferrini, G, Franzé, G, Frosini, G, Gaia, E, Galeazzi, R, Giaccari, S, Giglio, A, Gioè, FP, Grassini, M, Graziadei, L, Gullini, S, La Barbera, M, Loriga, P, Luisi, T, Magalini, M, Magrì, G, Maiolo, P, Malesci, A, Manildo, M, Marchi, S, Maurano, A, Mercati, U, Michetti, P, Milesi, F, Molinari, F, Morini, S, Nanfitò, L, Novelli, G, Olivari, N, Oliverio, F, Pacini, F, Pallio, S, Pasquini, G, Paterlini, A, Pera, A, Perego, M, Pracanica, G, Prada, A, Privitera, U, Recchia, S, Riegler, G, Rizzetto, M, Rocca, F, Roda, E, Romano, M, Rubbiani, M, Russo, A, Saggioro, A, Savarino, V, Scarpulla, G, Schiavone, C, Spotti, D, Sturniolo, G, Suriani, R, Surrenti, C, Usai, P, Verdianelli, G, Verros, G, Vigneri, S, Zambelli, A & Zaninotto, G 2005, 'Costo sociale annuo della dispepsia funzionale dopo l'eradicazione dell'Helicobacter pylori. Risultati di un'indagine in centri di endoscopia digestiva', PharmacoEconomics - Italian Research Articles, vol. 7, no. 1, pp. 27-42.
Colombo, Giorgio Lorenzo ; Caruggi, M. ; Vinci, M. ; Nardini, P. ; Casalini, S. ; Adamo, S. ; Amuso, M. ; Angioli, D. ; Bagnalasta, G. ; Benedetti, G. ; Bianchi Porro, G. ; Biagini, M. ; Bigazzi, U. ; Bodini, P. ; Briglia, R. ; Brosolo, P. ; Budillon, G. ; Candela, A. ; Capria, A. ; Capurso, L. ; Cardelli, A. ; Casale, V. ; Casetti, T. ; Cattaneo, D. ; Cerrai, F. ; Cesaroni, R. ; Chilovi, F. ; Corinaldesi, R. ; Craxì, A. ; Curzio, M. ; D'Ambrosi, A. ; D'Ambruoso, V. ; D'Ayala Valva, M. ; De Blasi, L. ; De Filippi, M. ; De Luca, B. ; De Spagnolis, B. ; Del Piano, M. ; Del Vecchio Blanco, C. ; Dell'Abate, P. ; Di Blasi, M. ; Di Stasi, M. ; D'Ingianna, E. ; Faleo, D. ; Ferrara, A. ; Ferrini, G. ; Franzé, G. ; Frosini, G. ; Gaia, E. ; Galeazzi, R. ; Giaccari, S. ; Giglio, A. ; Gioè, F. P. ; Grassini, M. ; Graziadei, L. ; Gullini, S. ; La Barbera, M. ; Loriga, P. ; Luisi, T. ; Magalini, M. ; Magrì, G. ; Maiolo, P. ; Malesci, A. ; Manildo, M. ; Marchi, S. ; Maurano, A. ; Mercati, U. ; Michetti, P. ; Milesi, F. ; Molinari, F. ; Morini, S. ; Nanfitò, L. ; Novelli, G. ; Olivari, N. ; Oliverio, F. ; Pacini, F. ; Pallio, S. ; Pasquini, G. ; Paterlini, A. ; Pera, A. ; Perego, M. ; Pracanica, G. ; Prada, A. ; Privitera, U. ; Recchia, S. ; Riegler, G. ; Rizzetto, M. ; Rocca, F. ; Roda, E. ; Romano, M. ; Rubbiani, M. ; Russo, A. ; Saggioro, A. ; Savarino, V. ; Scarpulla, G. ; Schiavone, C. ; Spotti, D. ; Sturniolo, G. ; Suriani, R. ; Surrenti, C. ; Usai, P. ; Verdianelli, G. ; Verros, G. ; Vigneri, S. ; Zambelli, A. ; Zaninotto, G. / Costo sociale annuo della dispepsia funzionale dopo l'eradicazione dell'Helicobacter pylori. Risultati di un'indagine in centri di endoscopia digestiva. In: PharmacoEconomics - Italian Research Articles. 2005 ; Vol. 7, No. 1. pp. 27-42.
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abstract = "Objective: The aim of this study was to evaluate socio-demographic and clinical characteristics of dyspeptic patients in Italy after the eradication of Helicobacter pylori infection and to evaluate the impact of this syndrome on daily activities, on loss of production, and, finally, to estimate its cost for both National Health Service and society. Design: An observational, prospective, one-year, multicenter study was conducted from April 1999 to April 2002 under the aegis of the Italian study group of digestive tract motility (GISMAD). The study was based on 577 consecutive functional dyspeptic patients after eradication of H. pylori. Data were collected by a Case Report Form (CRF). Setting: 91 Centres of Digestive Endoscopy (CED), all located in Italy. Results: The mean age of the 577 dyspeptic patients enrolled in the study was 52 yrs.±14 (13.3{\%} was younger than 40 yrs old; mostly females: 56.7{\%}). Sixty point seven percent of patients met expenses related with the treatment of dyspepsia. Patients were stratified into four groups according to their prevalent symptoms: ulcer-like (UL), dismotility-like (DL), reflux-like (RL) and 'other'. Annual mean cost estimated for each patient was € 145.54, with differences between females and males ( € 168.95 vs € 114.91 respectively). {"}RL{"} patients resulted at the highest cost (€ 204.32). Total costs were divided into health related costs (€ 60.87) and loss of productivity (€ 84.67), the latter being mostly related absences (21{\%}). Conclusions: During a follow-up period of 12 months, in each group there was a clear evidence of both a reduction of negative influence of dyspeptic symptoms on the patients' activities and a decrease of the mean cost for the treatment of dyspepsia. {"}RL{"} group presents cost 30{\%} higher when compared with {"}UL{"} and {"}DL{"} groups, and 90{\%} higher when compared with {"}other{"}.",
author = "Colombo, {Giorgio Lorenzo} and M. Caruggi and M. Vinci and P. Nardini and S. Casalini and S. Adamo and M. Amuso and D. Angioli and G. Bagnalasta and G. Benedetti and {Bianchi Porro}, G. and M. Biagini and U. Bigazzi and P. Bodini and R. Briglia and P. Brosolo and G. Budillon and A. Candela and A. Capria and L. Capurso and A. Cardelli and V. Casale and T. Casetti and D. Cattaneo and F. Cerrai and R. Cesaroni and F. Chilovi and R. Corinaldesi and A. Crax{\`i} and M. Curzio and A. D'Ambrosi and V. D'Ambruoso and {D'Ayala Valva}, M. and {De Blasi}, L. and {De Filippi}, M. and {De Luca}, B. and {De Spagnolis}, B. and {Del Piano}, M. and {Del Vecchio Blanco}, C. and P. Dell'Abate and {Di Blasi}, M. and {Di Stasi}, M. and E. D'Ingianna and D. Faleo and A. Ferrara and G. Ferrini and G. Franz{\'e} and G. Frosini and E. Gaia and R. Galeazzi and S. Giaccari and A. Giglio and Gio{\`e}, {F. P.} and M. Grassini and L. Graziadei and S. Gullini and {La Barbera}, M. and P. Loriga and T. Luisi and M. Magalini and G. Magr{\`i} and P. Maiolo and A. Malesci and M. Manildo and S. Marchi and A. Maurano and U. Mercati and P. Michetti and F. Milesi and F. Molinari and S. Morini and L. Nanfit{\`o} and G. Novelli and N. Olivari and F. Oliverio and F. Pacini and S. Pallio and G. Pasquini and A. Paterlini and A. Pera and M. Perego and G. Pracanica and A. Prada and U. Privitera and S. Recchia and G. Riegler and M. Rizzetto and F. Rocca and E. Roda and M. Romano and M. Rubbiani and A. Russo and A. Saggioro and V. Savarino and G. Scarpulla and C. Schiavone and D. Spotti and G. Sturniolo and R. Suriani and C. Surrenti and P. Usai and G. Verdianelli and G. Verros and S. Vigneri and A. Zambelli and G. Zaninotto",
year = "2005",
language = "Italian",
volume = "7",
pages = "27--42",
journal = "PharmacoEconomics - Italian Research Articles",
issn = "1590-9158",
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TY - JOUR

T1 - Costo sociale annuo della dispepsia funzionale dopo l'eradicazione dell'Helicobacter pylori. Risultati di un'indagine in centri di endoscopia digestiva

AU - Colombo, Giorgio Lorenzo

AU - Caruggi, M.

AU - Vinci, M.

AU - Nardini, P.

AU - Casalini, S.

AU - Adamo, S.

AU - Amuso, M.

AU - Angioli, D.

AU - Bagnalasta, G.

AU - Benedetti, G.

AU - Bianchi Porro, G.

AU - Biagini, M.

AU - Bigazzi, U.

AU - Bodini, P.

AU - Briglia, R.

AU - Brosolo, P.

AU - Budillon, G.

AU - Candela, A.

AU - Capria, A.

AU - Capurso, L.

AU - Cardelli, A.

AU - Casale, V.

AU - Casetti, T.

AU - Cattaneo, D.

AU - Cerrai, F.

AU - Cesaroni, R.

AU - Chilovi, F.

AU - Corinaldesi, R.

AU - Craxì, A.

AU - Curzio, M.

AU - D'Ambrosi, A.

AU - D'Ambruoso, V.

AU - D'Ayala Valva, M.

AU - De Blasi, L.

AU - De Filippi, M.

AU - De Luca, B.

AU - De Spagnolis, B.

AU - Del Piano, M.

AU - Del Vecchio Blanco, C.

AU - Dell'Abate, P.

AU - Di Blasi, M.

AU - Di Stasi, M.

AU - D'Ingianna, E.

AU - Faleo, D.

AU - Ferrara, A.

AU - Ferrini, G.

AU - Franzé, G.

AU - Frosini, G.

AU - Gaia, E.

AU - Galeazzi, R.

AU - Giaccari, S.

AU - Giglio, A.

AU - Gioè, F. P.

AU - Grassini, M.

AU - Graziadei, L.

AU - Gullini, S.

AU - La Barbera, M.

AU - Loriga, P.

AU - Luisi, T.

AU - Magalini, M.

AU - Magrì, G.

AU - Maiolo, P.

AU - Malesci, A.

AU - Manildo, M.

AU - Marchi, S.

AU - Maurano, A.

AU - Mercati, U.

AU - Michetti, P.

AU - Milesi, F.

AU - Molinari, F.

AU - Morini, S.

AU - Nanfitò, L.

AU - Novelli, G.

AU - Olivari, N.

AU - Oliverio, F.

AU - Pacini, F.

AU - Pallio, S.

AU - Pasquini, G.

AU - Paterlini, A.

AU - Pera, A.

AU - Perego, M.

AU - Pracanica, G.

AU - Prada, A.

AU - Privitera, U.

AU - Recchia, S.

AU - Riegler, G.

AU - Rizzetto, M.

AU - Rocca, F.

AU - Roda, E.

AU - Romano, M.

AU - Rubbiani, M.

AU - Russo, A.

AU - Saggioro, A.

AU - Savarino, V.

AU - Scarpulla, G.

AU - Schiavone, C.

AU - Spotti, D.

AU - Sturniolo, G.

AU - Suriani, R.

AU - Surrenti, C.

AU - Usai, P.

AU - Verdianelli, G.

AU - Verros, G.

AU - Vigneri, S.

AU - Zambelli, A.

AU - Zaninotto, G.

PY - 2005

Y1 - 2005

N2 - Objective: The aim of this study was to evaluate socio-demographic and clinical characteristics of dyspeptic patients in Italy after the eradication of Helicobacter pylori infection and to evaluate the impact of this syndrome on daily activities, on loss of production, and, finally, to estimate its cost for both National Health Service and society. Design: An observational, prospective, one-year, multicenter study was conducted from April 1999 to April 2002 under the aegis of the Italian study group of digestive tract motility (GISMAD). The study was based on 577 consecutive functional dyspeptic patients after eradication of H. pylori. Data were collected by a Case Report Form (CRF). Setting: 91 Centres of Digestive Endoscopy (CED), all located in Italy. Results: The mean age of the 577 dyspeptic patients enrolled in the study was 52 yrs.±14 (13.3% was younger than 40 yrs old; mostly females: 56.7%). Sixty point seven percent of patients met expenses related with the treatment of dyspepsia. Patients were stratified into four groups according to their prevalent symptoms: ulcer-like (UL), dismotility-like (DL), reflux-like (RL) and 'other'. Annual mean cost estimated for each patient was € 145.54, with differences between females and males ( € 168.95 vs € 114.91 respectively). "RL" patients resulted at the highest cost (€ 204.32). Total costs were divided into health related costs (€ 60.87) and loss of productivity (€ 84.67), the latter being mostly related absences (21%). Conclusions: During a follow-up period of 12 months, in each group there was a clear evidence of both a reduction of negative influence of dyspeptic symptoms on the patients' activities and a decrease of the mean cost for the treatment of dyspepsia. "RL" group presents cost 30% higher when compared with "UL" and "DL" groups, and 90% higher when compared with "other".

AB - Objective: The aim of this study was to evaluate socio-demographic and clinical characteristics of dyspeptic patients in Italy after the eradication of Helicobacter pylori infection and to evaluate the impact of this syndrome on daily activities, on loss of production, and, finally, to estimate its cost for both National Health Service and society. Design: An observational, prospective, one-year, multicenter study was conducted from April 1999 to April 2002 under the aegis of the Italian study group of digestive tract motility (GISMAD). The study was based on 577 consecutive functional dyspeptic patients after eradication of H. pylori. Data were collected by a Case Report Form (CRF). Setting: 91 Centres of Digestive Endoscopy (CED), all located in Italy. Results: The mean age of the 577 dyspeptic patients enrolled in the study was 52 yrs.±14 (13.3% was younger than 40 yrs old; mostly females: 56.7%). Sixty point seven percent of patients met expenses related with the treatment of dyspepsia. Patients were stratified into four groups according to their prevalent symptoms: ulcer-like (UL), dismotility-like (DL), reflux-like (RL) and 'other'. Annual mean cost estimated for each patient was € 145.54, with differences between females and males ( € 168.95 vs € 114.91 respectively). "RL" patients resulted at the highest cost (€ 204.32). Total costs were divided into health related costs (€ 60.87) and loss of productivity (€ 84.67), the latter being mostly related absences (21%). Conclusions: During a follow-up period of 12 months, in each group there was a clear evidence of both a reduction of negative influence of dyspeptic symptoms on the patients' activities and a decrease of the mean cost for the treatment of dyspepsia. "RL" group presents cost 30% higher when compared with "UL" and "DL" groups, and 90% higher when compared with "other".

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UR - http://www.scopus.com/inward/citedby.url?scp=20044365057&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:20044365057

VL - 7

SP - 27

EP - 42

JO - PharmacoEconomics - Italian Research Articles

JF - PharmacoEconomics - Italian Research Articles

SN - 1590-9158

IS - 1

ER -