Yellow nail syndrome and bilateral cystic lung disease

O. Sacco, B. Fregonese, C. E. Marino, G. Mattioli, C. Gambini, G. A. Rossi

Research output: Contribution to journalArticlepeer-review


In patients with yellow nail syndrome (YNS), highly characteristic nail changes are often associated with lymphedema and respiratory disorders due to pleural effusions or bronchiectasis. We describe a 4-year-old girl with the YNS who also had cystic lesions of the lung, affecting first the left lower lobe and, after surgical resection of the involved segments, also the right lower lobe. We discuss the etiology of the pulmonary cysts and hypothesize that abnormalities in pulmonary lymphatic flow, characteristic of YNS, may have decreased lung tissue compliance and determined the unusual progression of the cystic lesions in this patient.

Original languageEnglish
Pages (from-to)429-433
Number of pages5
JournalPediatric Pulmonology
Issue number6
Publication statusPublished - 1998


  • Adenomatoid malformation
  • Congenital cystic
  • Cystic lung lesions
  • Lymph flow
  • Yellow nail syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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