Yield of nuclear scan strategy in chest pain unit evaluation of special populations

Alberto Conti, Simone Vanni, Lucia Sammicheli, Serena Raveggi, Alberto Camaiti, Filippo Pieralli, Carlo Nozzoli, Chiara Gallini, Egidio Costanzo, Gian Franco Gensini

Research output: Contribution to journalArticlepeer-review


Background: Patients with chest pain (CP) and nondiagnostic ECG represent heterogeneous population in whom the evaluation of coronary risk factors including metabolic syndrome (MetS) and diabetes mellitus (DM) might improve risk stratification. Methods: We enrolled 798 consecutive CP patients; 14% presented with MetS and 10% with DM; the remaining 76% presented with other coronary risk profiles (others). All patients underwent maximal exercise tolerance test (ETT) and myocardial perfusion imaging (exercise-MPI). Those with positive testing underwent angiography, whereas the remaining patients were discharged and later followed up. Primary end-point was a composite of coronary stenoses greater than or equal to 50% documented by angiography or coronary events at follow-up. Results: Patients with MetS or DM had significantly lower survival free from end-point than those patients without (P96%); however, positive predictive value was 69, 74, and 52%, respectively (P

Original languageEnglish
Pages (from-to)1106-1112
Number of pages7
JournalNuclear Medicine Communications
Issue number12
Publication statusPublished - Dec 2008


  • Chest pain
  • Chest pain unit
  • Coronary artery disease
  • Diabetes mellitus
  • Exercise stress testing
  • Metabolic syndrome
  • Myocardial perfusion imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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