Zinc-dependent chemotactic defect in an infant with acrodermatitis

L. Businco, A. M. Menghi, P. Rossi, R. D'Amelio, E. Galli

Research output: Contribution to journalArticlepeer-review


A 5-month-old infant developed acrodermatitis enteropathica when weaned from breast milk to cows' milk. Plasma zinc concentration was low. T- and B-lymphocyte functions were normal, but there was a severe defect of neutrophil chemotaxis. Oral treatment with zinc sulphate (40 mg daily) induced an immediate clinical improvement, with restoration of normal plasma zinc level and complete correction of neutrophil chemotaxis.

Original languageEnglish
Pages (from-to)966-968
Number of pages3
JournalArchives of Disease in Childhood
Issue number12
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Allergy
  • Pediatrics, Perinatology, and Child Health


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