Zinc homeostasis in aging: Two elusive faces of the same "metal"

Eugenio Mocchegiani, Laura Costarelli, Robertina Giacconi, Catia Cipriano, Elisa Muti, Lothar Rink, Marco Malavolta

Research output: Contribution to journalArticlepeer-review


Proteins involved in zinc homeostasis may be altered in aging. This phenomenon may lead to zinc deficiency in the peripheral blood and an accumulation of zinc bound to insoluble aggregates at the extracellular level in the brain. Therefore, it should be more correct to talk about aging as a condition associated with zinc dyshomeostasis rather than deficiency. Restoring functional zinc homeostasis in aging people is an attractive field for antiaging research, but requires further knowledge than the current state of the art.

Original languageEnglish
Pages (from-to)351-354
Number of pages4
JournalRejuvenation Research
Issue number2
Publication statusPublished - Jun 2006

ASJC Scopus subject areas

  • Ageing


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