TY - JOUR
T1 - Zinc homeostasis in aging
T2 - Two elusive faces of the same "metal"
AU - Mocchegiani, Eugenio
AU - Costarelli, Laura
AU - Giacconi, Robertina
AU - Cipriano, Catia
AU - Muti, Elisa
AU - Rink, Lothar
AU - Malavolta, Marco
PY - 2006/6
Y1 - 2006/6
N2 - Proteins involved in zinc homeostasis may be altered in aging. This phenomenon may lead to zinc deficiency in the peripheral blood and an accumulation of zinc bound to insoluble aggregates at the extracellular level in the brain. Therefore, it should be more correct to talk about aging as a condition associated with zinc dyshomeostasis rather than deficiency. Restoring functional zinc homeostasis in aging people is an attractive field for antiaging research, but requires further knowledge than the current state of the art.
AB - Proteins involved in zinc homeostasis may be altered in aging. This phenomenon may lead to zinc deficiency in the peripheral blood and an accumulation of zinc bound to insoluble aggregates at the extracellular level in the brain. Therefore, it should be more correct to talk about aging as a condition associated with zinc dyshomeostasis rather than deficiency. Restoring functional zinc homeostasis in aging people is an attractive field for antiaging research, but requires further knowledge than the current state of the art.
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U2 - 10.1089/rej.2006.9.351
DO - 10.1089/rej.2006.9.351
M3 - Article
C2 - 16706668
AN - SCOPUS:33744965484
VL - 9
SP - 351
EP - 354
JO - Rejuvenation Research
JF - Rejuvenation Research
SN - 1549-1684
IS - 2
ER -