Zoster... "almost"... sine herpete: Diagnostic utility of real time-polymerase chain reaction

Gino A. Vena, Doriana Apruzzi, Michelangelo Vestita, Agata Calvario, Caterina Foti, Nicoletta Cassano

Research output: Contribution to journalArticlepeer-review


Zoster sine lierpete is a particular form of varicella zoster virus (VZV) infection characterized by segmental pain and dysesthesia, without any cutaneous lesions ever becoming perceptible. This report describes the case of a female patient, presenting with intercostal pain associated with a single papulo-vesicular lesion localized within the same area. Thanks to such a lesion, real time-polymerase chain reaction (PCR) analysis on vesicle fluid swab was possible, thus revealing a significant number of VZV genome copies. This innovative tool has proven essential to diagnose this abortive form of herpes zoster, which would otherwise have remained unidentified.

Original languageEnglish
Pages (from-to)409-410
Number of pages2
JournalNew Microbiologica
Issue number4
Publication statusPublished - Oct 2010


  • Herpes zoster virus
  • Polymerase chain reaction
  • Zoster sine herpete

ASJC Scopus subject areas

  • Microbiology (medical)

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